Man muss nach englischen Artikeln suchen, am besten auf scholar.google.de
Das ist ein Ausschnitt aus einem
offenen Brief von Dr. Schultz:
"There is excellent evidence for lifelong immunity to CDV, CPV-2, and CAV-1 in the dog, and FPV in the cat. This is similar to the lifelong immunity to measles, mumps, and rubella after childhood vaccination. Of course, this requires that the dog, cat, or human was appropriately vaccinated and immunized! When vaccines are shown to provide at least 3 or more years of immunity in a dog or cat, which all of the current major manufacturers’ CDV/CPV-2/CAV-2 for the dog and FPV for the cat have shown, that is equivalent to lifelong in a species that lives an average of 10 to 15 years, just as 20 to 30 years for a human vaccine is evidence that it will provide lifelong immunity. However, there have been many studies based both on challenge and antibody
titer showing that antibody and protective immunity persist for over 7 years for current canine and feline core vaccines in the absence of revaccination and absence of the viruses. References for those studies were sent to Dr. Lahey. Similarly, antibody can be shown to persist in humans to MMR for a lifetime in the absence of overt revaccination. This long-lived immunity in dogs, cats, and humans occurs as a result of long-lived plasma cells. Obviously, this long-lived immunity is not seen after all vaccinations: for example, protection from Leptospira, Borrelia (Lyme), or Bordetella is generally considered to be a year, plus or minus a few months. Whenever it can be shown that recovery from natural infection, which leads to natural immunization, provides lifelong immunity, we should be able to make a vaccine that can also provide lifelong immunity! Likewise, if natural immunization only provides 1 or 2 years of immunity, you won’t be able to make a vaccine that provides lifelong immunity."
Das ist ein sehr ausführlicher Artikel:
http://www.bettercaninehealth.org.uk/uploads/9/2/5/1/9251386/long_term_protective_immunity.pdf
